Amplification and Detection

In molecular diagnostics, the amplification and detection of genetic material enable pathogens to be identified quickly.

Why it’s important

Amplification enables the genetic target to be multiplied and thus increases detection sensitivity.

  • This step makes it possible to detect tiny quantities of infectious agents that traditional methods would be unable to detect.

Detection of copies resulting from amplification is made possible by small molecules known as probes, designed to bind to the target if it is present in the sample.

  • These probes release a fluorescent signal that reveals certain pathogens or variations in genes.
  • Through the use of probes with different fluorescent markers, several genetic targets can be detected simultaneously in a single sample.

bioMérieux's product offering

bioMérieux's systems use PCR (Polymerase Chain Reaction) technology, as well as real-time NASBA® (Nucleic Acid Sequence-Based Amplification) technology.

Our ARGENE® SOLUTION and NUCLISENS EASYQ® ranges cover a broad panel of tests for the detection and amplification of viral genomes. These tests can be used to establish a diagnosis, conduct preventive screening, and monitor the effects of certain treatments.

Our ARGENE® SOLUTION offering is a comprehensive automated solution dedicated to centralized laboratories for the management of molecular biology tests to monitor viral infections in immunocompromized patients.

This solution is made up of several items: 

  • Our extraction systems EMAG® and NucliSENS EasyMAG®
  • The ARGENE® range of high medical value tests,  particularly well-suited to the monitoring of immunocompromised patients.The range includes PCR kits for the detection of:
    • herpesvirus,
    • Epstein-Barr virus,
    • cytomegalovirus,
    • adenovirus,
    • enterovirus,
    • infectious respiratory viruses

Our automated platform NUCLISENS EASYQ® for the real-time amplification and monitoring of VIH viral load, can process up to 48 samples in less than 90 minutes.