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New-Generation Mass Spectrometry Microbial Identification System

VITEK® MS PRIME combines microbiology expertise with innovation taking mass spectrometry to the next level by maximizing the impact of daily laboratory workflow for better patient care. 


Disclaimer: Product availability varies by country. Please consult your local bioMérieux representative for product availability in your country. 

System Overview


Take your MALDI-TOF** mass spectrometry to the next level! The VITEK® MS PRIME system is designed for routine microbial identification and enhances laboratory workflow efficiency and productivity for faster time to results and improved patient management.

Superior Workflow Efficiency for easy integration, improved ergonomics, full traceability, greater productivity, and faster time to reported results: 
  • Benchtop system with on-board PC, adjustable monitor, and integrated keyboard to easily integrate into the lab environment and workflow
  • Automated continuous Load & Go: capacity up to 16 slides and 768 samples, end-to-end sample traceability with automatic barcode scanning, unload slides individually or by batch on demand
  • Urgent slide prioritization in one click for critical patient samples without impact on the slide currently processed
  • One fast and easy protocol per organism group for sample preparation
  • User friendly flexible setup and results review

Robust and Evolving Database for enhanced customer confidence, faster time to reported results, easier adoption, and technician time savings: 

  • Faster and accurate ID results within minutes using a robust IVD database that is regularly updated with new emerging pathogens, clinically relevant species, and taxonomy changes
  • An average of 10-12 strains per species to represent microbial variability
  • Single choice results with differentiation between closely related species

Fully Integrated ID & AST Solution for easier implementation in the lab, time & cost savings, and consistent, actionable reporting:

  • Seamless updates, connectivity and integration with VITEK® 2 thanks to MAESTRIA™ middleware to support earlier optimized antimicrobial therapy
  • Lab data transformed into actionable insights with MAESTRIA™ and CLARION™ Lab Analytics to support epidemiology and surveillance

A Committed Service Partner with 60+ years of microbiology expertise to maximize system uptime and free up lab staff’s time spent on maintenance: 

  • All-new inside: lifetime laser, innovative ion optics, and new linear detector for greater lab productivity
  • Automated Fine Tuning for maximum uptime: initiates when the instrument is not in use

Helping Your Lab Make a Difference in AMS

In a world of ever-challenging Antimicrobial Resistance, bioMérieux is your committed partner for Antimicrobial Stewardship (AMS). By putting diagnostics at the heart of AMS, labs help drive informed decisions.

VITEK® MS PRIME further strengthens your lab capacity to support AMS by:

  • Reporting ID results faster to optimize antibiotic therapy earlier
  • Providing targeted therapy when combined with VITEK® 2, offering a complete and seamless integration for same-day ID/AST results


*As compared to VITEK MS®

**Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Discover the benefits of VITEK® MS PRIME

Available Reagents

All VITEK® MS reagents and accessories are ready-to-use for easy adoption with VITEK® MS PRIME. Reagent kits contain all reagents needed for ID testing and no extra reagent preparation time is required.  

  • VITEK® PICKME™ makes sample preparation easier, streamlined, and more standardized reducing repeat tests.
  • VITEK® MS-DS disposable target slides have a unique barcode identifier to ensure end-to-end traceability. No slide cleaning required, meaning elimination of possible contamination that could lead to erroneous results or safety issues.
  • VITEK® MS-CHCA matrix is a ready-to-use, light stable matrix solution (CHCA) that saves time on reagent preparation. 
  • VITEK® MS-FA is formic acid needed for yeast and fungi. It is ready-to-use with no dilution required and already allocated in small vials.
  • VITEK® MS Mycobacterium/ Nocardia and Mould reagent kits contain all reagents and consumables necessary for simple inactivation and extraction for identification of these organisms.
  • VITEK® MS SMARTCALIBRANT further optimizes the workflow of VITEK® MS PRIME to streamline daily preparation of calibration spots. Its ready-to-use liquid format reduces hands-on time and provides a standardized E.coli deposit when calibrating.

Services & Support 

By Your Side from Installation and Integration to Daily Operations 

VITEK® MS PRIME is part of a comprehensive service offering from consultancy to installation and connectivity through training, verification, workflow optimization, and ongoing support.

System Services

To provide you with the highest level of customer service, training, and support we have two dedicated teams to answer your everyday questions and needs:

  • Local subsidiary teams
  • Global Customer Service (GCS)

Every bioMérieux subsidiary and distributor has its own Local Customer Service to ensure support is close at hand. Our objective is to ensure you receive first class personalized service regardless of your geographical location.

These local teams can rely on global level teams, which have an international vision of the in vitro diagnostics market, for extra support when required on instruments, reagents, information technology, and service solutions.

Learning Services

bioMérieux wants to make your life easier. Login or Register to our new Resource Center website. Here you can access Quality Control Certificates (QCC), Instructions For Use (IFU), and System Manuals along with other file types.


Logistic Services

We can help optimize your logistics to increase operational efficiency, allowing you to refocus on your core expertise. We know how to optimize supply operations, prevent shortage and waste, and monitor your supply performance for optimal results. 

We will work alongside you to simplify your supplies and guarantee the availability of key products, ensuring the efficient continuity of your activities. We serve customers in more than 160 countries, and process 1 million orders per year. Our experts prepare and ship your order in full compliance with the strictest regulatory and quality standards. 



Collaborative every step of the way, we bring you customizable services that help you create the balance that makes the most of your lab talent and expertise. To really get to know your lab, we “roll up our sleeves” and work by your side to:

  • Support rapid decisions
  • Increase productivity
  • Maximize quality

When we combine your knowledge of your lab and our expert outside perspective, we have the winning formula to enhance use of technology, improve workflow and processes, and make the most of staff skills.



Cybersecurity is integrated into the design of VITEK® MS PRIME and includes continued surveillance by our security experts.

System Services

Systems are a major investment for your lab. Night and day, you depend on them to help you provide clinicians with fast, reliable results for better patient care. With System Services from bioMérieux: maximize routine lab workflow, cover increased productivity needs, and deliver high quality patient results confidently and continuously.

Specs & Resources

Technical Specifications 

Capacity: Up to 16 slides and 768 samples

VITEK MS PRIME Technical Specifications

Population-built, the database allows for better discrimination between species and accounts for diversity among strains within the same species.

  • Geographical diversity of isolates
  • Isolates of different origins
  • Isolates subcultured on different media and from different incubation times

The VITEK® MS PRIME database is consistently expanding to bring new emerging pathogens and clinically relevant species such as Mycobacterium intracellulare ssp chimaera. The VITEK® MS PRIME Knowledge Base (KB) update Version 3.3 includes new bacteria and fungi focusing on anaerobes, mycobacteria, nocardia, and molds and includes taxonomy updates based on current nomenclature.


VITEK® MS PRIME with SARAMIS®: a flexible and broad database for Research and Routine

  • Ability to create a customized RUO database 
  • One common sample preparation for IVD & RUO analysis
  • Unique software for easy setup of IVD or RUO samples 
  • Direct transfer of spectra possible from the IVD database to the RUO database with one click




VITEK® MS PRIME Reagent Brochure 




Wattal C, Oberoi JK, Goel N, Raveendran R, Khanna S. Matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) for rapid identification of micro-organisms in the routine clinical microbiology laboratory. EurJ Clin Microbiol Infect Dis. 2017

Bardelli M, et al. A side-by-side comparison of the performance and time-and-motion data of VITEK® MS. EurJ Clin MicrobiolInfect Dis, 2022

Grohs P, Remaud E, Lath C, et al. Comparison of the New VITEK MS PRIME System with the Matrix-Assisted Laser Desorption Ionization Biotyper Microflex LT for the Identification of Microorganisms. Ann Lab Med. 2023;43(6):574-584