As pathogens change over time, they can become resistant to antibiotics, making it more difficult to treat infections that may lead to sepsis. This ongoing growth of antimicrobial-resistant bacteria continues to pose a threat to public health. We sat down for a virtual interview with Eric R. Wenzler, PharmD, BCPS, BCIDP, AAHIVP, Assistant Professor in the Department of Pharmacy Practice at the University of Illinois at Chicago College of Pharmacy, to learn more about the role of diagnostics and stewardship intervention when caring for sepsis patients.