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ETEST®

Antibiotic Susceptibility Testing Reagent Strips to Determine On-Scale MICs 

Clinicians often need more information than what primary AST can provide. Recognized around the world for their proven performance, ETEST® ready to use reagent strips determine on-scale MICs.

  

  

  

  

Disclaimer: Product availability varies by country. Please consult your local bioMérieux representative for product availability in your country. 

Overview

Proven Medical Value in the Face of Growing Resistance

ETEST® strips is the original gradient MIC strips. The strips consistently maintain their reliability when it comes to establishing the on-scale Minimum Inhibitory Concentration (MIC) of antibiotics and antifungal agents. ETEST® is a predefined, stable gradient of 15 antimicrobial concentrations on a plastic strip. ETEST® has an extensive range of over 90 antimicrobial references available in the following categories: antibiotics, antifungals, and antimicrobial resistance detection (ARD).

 

ETEST® is a simple, cost-effective tool that offers MIC results to complement your routine antimicrobial susceptibility tests (AST) performed on VITEK® 2  systems, or other automated platforms or manual testing (Kirby-Bauer method) allowing you to:

 

  • Test new/non-routine antimicrobials
  • Determine the MIC of fastidious, or slow-growing micro-organisms
  • Confirm or detect low-level or new resistance mechanisms
  • Fine-tune antimicrobial treatment

 

  

The Trusted Original Gradient MIC Strips

The original gradient MIC strip of its kind, ETEST® continues to grow. Its documented performance has reinforced its position as a reliable leader in the gradient MIC strip market.

 

 

 

Did you know?

references

>4,000 Scientific References from 50 Countries

15 ETEST® Strips Performed Every Minute

Global Customer Accessibility in >120 Countries

Versatile & Flexible: The Method of Choice to Supplement Your Main Primary Routine AST System

Most clinical laboratories use commercially available automated AST systems, such as VITEK® or disk diffusion as a primary means of AST. However, primary AST testing does not cover 100% of AST needs.

 

ETEST® is an accurate solution for completing the AST profile:

 

  • For new antimicrobials that are not accessible in a routine mode
  • For difficult organisms that can’t be tested by primary AST methods (e.g., fastidious, anaerobic, primary AST limitations, etc.) 
  • For drug/bug combinations that are not available 

 

ETEST® fills gaps that primary testing cannot cover:

 

  • Detecting low levels of resistance or new resistance mechanisms 
  • Fine-tuning antimicrobials treatment (MDROs, drug with narrow therapeutic index, critically ill patients, breakpoints zone, or ATU)
  • Detecting or confirming antimicrobial resistant phenotypes such as ESBL, MBL, AmpC*, or GISA/hGISA*

 

*For Research Use Only

 

Extended-Range MICs Spanning 15 Two-Fold Dilutions 

ETEST® provides full-range MICs spanning 15 two-fold dilutions for concentrations that are ideal for refining patient treatment in instances where routine AST methods are limited in one of the following ways:

  • Provides S, I, or R category results only
  • MIC results are off-scale (i.e., “<” or “>” results) and do not provide sufficient data for pharmacokinetic/pharmacodynamic (PK-PD) targeted dosing considerations

Easy-to-Use MIC Technique

ETEST® is easy to implement and use:

  • No software or specific skills required
  • Individual testing – perfectly adapted for MIC testing for newly launched antimicrobials

  

ETEST® Aztreonam/Avibactam (AZA)

Test strips rapidly, easily determine MIC level for Aztreonam/Avibactam susceptibility for Enterobacterales*.

Provide vital information for appropriate therapy decision for complicated infections** and to help reduce development of drug-resistant bacteria.

Making sure that patients get the right antimicrobial, in the right dose, at the right time is at the heart of antimicrobial stewardship.

  • Confidence: Reliably monitor efficacy Aztreonam/Avibactam of  treatment for complicated infections
  • Fast time to result: 16 hours
  • Accuracy: Determine exact Minimum Inhibitory Concentration (MIC) values of Aztreonam/Avibactam

Aztreonam/Avibactam, known by the trade name EMBLAVEO®, is used to treat certain multidrug-resistant Gram-negative infections. It is indicated for complicated intraabdominal infections (cIAI), hospital-acquired pneumonia (HAP), including ventilatorassociated pneumonia (VAP), complicated urinary tract infections (cUTI), including pyelonephritis, and infections due to aerobic Gram-negative organisms with limited treatment options.

ETEST® AZA was developed by bioMérieux in collaboration with Pfizer, the producer of EMBLAVEO®.

ETEST® AZA (0.016/4-256/4 μg/mL)
REFERENCE : 424460 - WW market (excl US)

*Enterobacterales: Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae complex, Citrobacter freundii complex, Klebsiella aerogenes, Proteus mirabilis, Proteus vulgaris, Citrobacter koseri, Morganella morganii, Serratia marcescens, Providencia stuartii

** complicated infections: complicated intraabdominal infections (cIAI), hospital-acquired pneumonia (HAP), including ventilatorassociated pneumonia (VAP), complicated urinary tract infections (cUTI), including pyelonephritis, and infections due to aerobic Gram-negative organisms with limited treatment options.

ETEST® SUD

ETEST® Sulbactam/Durlobactam (SUD) is a reliable new tool for Sulbactam/Durlobactam susceptibility testing in Acinetobacter baumannii-calcoaceticus complex.

Developed with our partner Innoviva™, ETEST® SUD aids in combating hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) caused by susceptible isolates of Acinetobacter baumannii-calcoaceticus complex.

This innovative solution provides a critical new option for managing CRAB (Carbapenem-Resistant Acinetobacter baumannii) infections, which was identified as a top priority by WHO due to its resistance and clinical challenges1.

ETEST® Sulbactam/Durlobactam (SUD) plays a vital role in guiding clinical decisions for effective treatment with Sulbactam/Durlobactam.

1. WHO Bacterial Priority Pathogens List, 2024: bacterial pathogens of public health importance to guide research, development and strategies to prevent and control antimicrobial resistance

Filename
Flyer-ETEST-SUD.pdf
Size
1 MB
Format
application/pdf
etest sud plate

ETEST® Sulbactam/Durlobactam (SUD) - (0.004/4-64/4 µg/mL)
REFERENCE: 423575 - WW market (excl. US)

ETEST® IRPA 

ETEST® Imipenem/Relebactam P. aeruginosa (IRPA) is a reliable new tool for Imipenem/Relebactam susceptibility testing of Pseudomonas aeruginosa.

Provide vital information for appropriate therapy decision for complicated infections where limited treatment options are available and to help reduce development of Pseudomonas aeruginosa Multi Drug Resistance (PA MDR). Making sure that patients get the right antimicrobial, in the right dose, at the right time is at the heart of antimicrobial stewardship.

Imipenem/Relebactam, known by the trade name RECARBRIO™, is used to treat certain multidrug-resistant Gram-negative infections. It is indicated for complicated intraabdominal infections (cIAI), hospital-acquired bacterial pneumonia (HABP), including ventilator-associated bacterial pneumonia (VABP), complicated urinary tract infections (cUTI), including pyelonephritis.

ETEST® IRPA was developed by bioMérieux in collaboration with Merck, the producer of RECARBRIO™.

This new ETEST® Imipenem/Relebactam P. aeruginosa (IRPA) complements our existing ETEST® Imipenem/Relebactam (IPR) already available for the testing of Enterobacterales*

*Enterobacterales : Citrobacter freundii, Enterobacter cloacae/Enterobacter cloacae complex, Escherichia coli, Klebsiella aerogenes, Klebsiella oxytoca, Klebsiella pneumoniae

1. WHO Bacterial Priority Pathogens List, 2024: bacterial pathogens of public health importance to guide research, development and strategies to prevent and control antimicrobial resistance

Filename
Flyer-ETEST-SUD.pdf
Size
1 MB
Format
application/pdf
etest sud plate

ETEST® IRPA (0.006/4-128/4 µg/mL)
REFERENCE : 424548 - WW market (excl US)

Specs & Resources

Specifications

ETEST® Strips:

  • Over 90 antimicrobials in the following categories: Antibiotics, Antifungals, and Antimicrobial Resistance Detection (ARD)
  • Easy to implement in most clinical laboratories. Ready-to-use AST 
  • Predefined, and stable antimicrobial gradient (dry chemistry) 
  • Inert, non-porous plastic strip
  • Agar-based method with its advantages (e.g.: identify contamination...)
  • Large scale (15 antimicrobial concentrations)
  • Half dilution, accurate on-scale MICs value
  • Performances validated against a reference method

  

ETEST® Packaging Designed by bioMérieux to Suit Your Needs

SINGLE PACK: 30 Strips 

  • Individual strips packaging, easy opening, adapted to the low testing volume
ETEST Reading Scale

MULTIPACK: 100 Strips

  • 10 cartridges of 10 strips, perfectly adapted to high-volume testing
ETEST Reading Scale

Resources

ETEST® Brochure

  

Testimonials