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Understanding the value of diagnostics

View the articles below to learn more about the importance of diagnostics in solving everyday healthcare challenges, optimizing patient care. 

  

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Five Lessons Learned About Antimicrobial Stewardship Metrics

Antimicrobial stewardship (AMS) metrics are essential for identifying, acting on, and re-evaluating opportunities to enhance the safe and appropriate use of antibiotics. Without reliable data, antibiotic stewards risk being ineffective.

The Power of Point-of-Care (POC) Testing in Respiratory Illnesses: Lessons from COVID-19 and the Fight Against AMR

Respiratory illnesses remain a major public health challenge, and the COVID-19 pandemic only magnified the need for fast, accurate diagnostic testing.

Five Years Later – How COVID-19 Transformed Clinical Laboratories

It’s been five years since the World Health Organization (WHO) declared COVID-19 a pandemic in March 2020. This global health crisis fundamentally reshaped clinical laboratories, accelerating advancements in diagnostic testing capabilities, capacity, and automation.

The Power of Point-of-Care (POC) Testing in Respiratory Illnesses: Lessons from COVID-19 and the Fight Against AMR

Respiratory illnesses remain a major public health challenge, and the COVID-19 pandemic only magnified the need for fast, accurate diagnostic testing.

Infographic: The Cascading Effects of Antimicrobial Resistance

Explore the systemic impacts of antimicrobial resistance (AMR) and the importance of implementing effective antimicrobial stewardship (AMS) strategies in this easy to understand infographic.

Viewpoints Series: Enhancing Sepsis Care Across the Patient Journey 

A recent survey by bioMérieux and The UK Sepsis Trust found that while 95% of clinicians identify sepsis as a serious condition, 66% agree there is sometimes a delay in diagnosis in the hospital where they work.

Transforming Diagnostics in GI Infections: The Role of Molecular Testing

Gain valuable insights into the pressing challenge of diagnosing gastrointestinal infections (GI) in the context of antimicrobial resistance (AMR)

Management and outcomes in pulmonary arterial hypertension patients with sepsis

A recent retrospective study examining sepsis treatment in patients with and without pulmonary arterial hypertension (PAH) reveals critical insights for clinical practice.

Not all carbapenem-resistant Pseudomonas aeruginosa strains are alike: tailoring antibiotic therapy based on resistance mechanisms

Antimicrobial resistance in Pseudomonas aeruginosa remains a serious health threat because multiple mechanisms may be involved that further complicate the management of infections.

Antimicrobial Stewardship: Integrating Diagnostics and Data-Driven Solutions for a Resilient Future

With the landscape of healthcare rapidly evolving, diagnostic innovation, health equity, and the strategic value of laboratory services are emerging as critical focal points.

Exclusion Diagnosis With Rapid PCR For Febrile Neonate 

Did you know that over 5 million people are affected by meningitis every year, and around half of all meningitis deaths are in children under 5 years old? ​

High-cost users after sepsis: a population-based observational cohort study

An observational study conducted in Canada and published in Critical Care reveals significant financial implications of sepsis on post-hospitalization patient care.

Microbiology testing capacity and antimicrobial drug resistance in surgical-site infections

Surgical-site infection (SSI) is one of the most common healthcare-associated infections (HAI) globally, and the most frequent postoperative complication

VIEWPOINTS SERIES: Lack of AMR Understanding May Compromise Diagnostic Potential

In recognition of World AMR Awareness Week (WAAW), this Viewpoints Series interview with pharmacist Jacob Morton explores the critical issue of limited public awareness about antimicrobial resistance (AMR) and its impact on patient healthcare.

Severe HAP due to Klebsiella pneumoniae resistant to carbapenems

Did you know that Hospital Acquired Pneumonia (HAP) is the second most common nosocomial infection and accounts for more than 50% of the antibiotics prescribed?​​

LL Editorial: Sepsis Care Diminished by Antimicrobial Resistance

Explore strategies for managing sepsis and AMR concurrently.

LL Editorial: Sepsis Care Diminished by Antimicrobial Resistance

Explore strategies for managing sepsis and AMR concurrently.

When the drugs don’t work: the people living with the reality of the superbugs crisis

Discover stories that highlight the realities faced by individuals battling superbugs and the vital role medical professionals play.

A case of Haemophilus influenzae meninigtis​

Did you know that elderly people are at higher risk of having acute bacterial meningitis associated with an earlier and higher mortality rate than in younger patients ?​​
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Do you have what it takes to be a Game Changer in the fight against infectious diseases and AMR?

Play MICROBE LEAP, bioMérieux’s interactive AMS game, to test your diagnostic knowledge and antimicrobial stewardship skills as a Patient Protector or Resistance Avenger!
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Do you have what it takes to be a Game Changer in the fight against infectious diseases and AMR?

Play MICROBE LEAP, bioMérieux’s interactive AMS game, to test your diagnostic knowledge and antimicrobial stewardship skills as a Patient Protector or Resistance Avenger!
microbe-leap-game-cover.png

Do you have what it takes to be a Game Changer in the fight against infectious diseases and AMR?

Play MICROBE LEAP, bioMérieux’s interactive AMS game, to test your diagnostic knowledge and antimicrobial stewardship skills as a Patient Protector or Resistance Avenger!

The history of AMR and the important role diagnostics plays to combat it

In this MLO feature article, Chris Groke, Senior Medical Science Liaison at bioMérieux, breaks down the history of diagnostic innovation in the fight against antimicrobial resistance (AMR). As a Board-Certified Infectious Diseases Pharmacist, Groke shares knowledge and insight into the evolution of AMR and the critical role diagnostics play in addressing this global public health threat.

India-based Alliance Paves the Way for Global Mitigation of Antimicrobial Resistance (AMR)

Fifty-two medical specialty organizations and associations from across India are taking on antimicrobial resistance (AMR), paving the way for low- to middle-income countries looking to mitigate the impact of AMR. The country recognizes the severe impact caused by neglecting AMR, with over a million deaths attributed to AMR-related complications each year.

Roundtable: Current Trends and Future Opportunities in Antimicrobial Stewardship through Diagnostic Innovations

The antimicrobial stewardship (AMS) landscape is rapidly changing and diagnostics are revolutionizing how medical professionals meet AMS goals. In this CIDRAP ASP webinar and roundtable, experts discuss insights and share personal experiences regarding diagnostic trends and emerging opportunities for AMS.

Native Joint Septic Arthritis

Did you know that bacterial arthritis is most common cause of pediatric septic arthritis in children with an incidence of 1-37 cases per 100,000 worldwide?​​

Global Economic Impacts of Antimicrobial Resistance

This groundbreaking study by Fernando and McKibbin employs sophisticated macroeconomic modeling to assess the global economic impacts of antimicrobial resistance (AMR) across G20 countries

Challenges in Sepsis Management  in Low and Middle Income Countries (LMICs)

Delve into the critical challenges of sepsis management in resource-limited settings with Professor Machado's insightful interview.

Antimicrobial Resistance Patterns of Outpatient Staphylococcus aureus Isolates

A retrospective analysis of 382,149 Staphylococcus aureus isolates from U.S. Veterans Health Administration outpatients reveals significant shifts in antimicrobial resistance patterns over a 10-year period.

Clinical Advances in Diagnostic and Antimicrobial Stewardship

This series covers advances in diagnostic and antimicrobial stewardship, focusing on multiplex PCR testing to combat MDROs and improve prescribing.

Severe Respiratory Failure In Patient With Aspergillus With Covid-19 Infection

Discover a clinical case illustrating how rapid multiplex PCR can support patient management and treatment in the context of a patient suffering from COVID-19 in the context of a co-infection with Aspergillus​

Future Opportunities in Antimicrobial Stewardship through Diagnostic Innovations

As part of a CIDRAP three-part webinar series, bioMérieux is proud to support this second installment that explores the shifting landscape of the rapid diagnostic laboratory, highlighting the transformative impact brought about by new technologies.

A paradigm shift in pneumonia management​

Discover a clinical case from Dr Naim Aoun highlighting the instrumental role of syndromic testing in managing critically ill patient within the intensive care unit. ​

Evaluating the Impact of Source-Specific Order Sets for Sepsis on Empiric Antibiotic Selection in the Emergency Department

A study shows source-specific antibiotic order sets in emergency care improve empiric treatment decisions for sepsis and support timely patient management.

Severe Hospital Acquired Pneumonia

Did you know that Hospital Acquired Pneumonia is the second most common nosocomial infection and accounts for more than 50% of the antibiotics prescribed?​​

VIEWPOINTS SERIES: Improved Antimicrobial Stewardship Needed in Latin America

Explore the need for improved antimicrobial stewardship in Latin America, highlighting AMR's impact.

Sepsis Alliance AMR Virtual Conference

The Sepsis Alliance AMR Virtual Conference explores innovative solutions and educational initiatives for managing sepsis and combating antimicrobial resistance.

Hospital Acquired Pneumonia for Trauma Patient

Did you know that Hospital Acquired Pneumonia is the second most common nosocomial infection and accounts for more than 50% of the antibiotics prescribed?​​

Ventilator Acquired Pneumonia

Did you know that Ventilator Acquired Pneumonia is associated with a 2-fold to 3-fold increase in mortality and morbidities?

VIEWPOINTS SERIES: ID Pharmacists Discuss AMS Survey Data | Part 1

Explore key insights from ID pharmacists on antimicrobial stewardship challenges, survey findings, and strategies for improving ASP implementation.

Using Identification And Antimicrobial Susceptibility Testing (ID/AST) To Reinvigorate Antimicrobial Stewardship

bioMérieux experts discuss how microbial identification and susceptibility testing can enhance antimicrobial stewardship and improve patient outcomes post-COVID.

Outcomes Research & AMR: A Human-Centered Perspective on a Biosocial Problem

CIDRAP-ASP explores AMR outcomes research through a socio-economic lens, emphasizing systems thinking and the integration of social sciences.

The BIOFIRE® Blood Culture Identification 2 (BCID2) Panel: Rapid Diagnostics For Improved Antimicrobial Stewardship And Patient Outcomes

The BIOFIRE® BCID2 Panel uses rapid PCR technology to identify pathogens and resistance genes, improving antimicrobial stewardship, patient outcomes, and reducing hospital stay.

Hidden Treasures In The Underwater Pharma-sea

Scientists explore ocean biodiversity, uncovering potential new drug-producing biosynthetic pathways from marine microbes to combat drug resistance.

Rapid Detection and Diagnostic Surveillance of Candida auris is Key as U.S. Rates Rise

Learn how rapid diagnostics and surveillance can help detect and prevent the spread of Candida auris as U.S. infection rates continue to rise.

Use Of Electronic Clinical Data To Track Incidence And Mortality For Sars-cov-2-associated Sepsis

EHR-based data shows SARS-CoV-2–associated sepsis was more severe and frequent than bacterial sepsis early in the pandemic, highlighting tracking gaps.

Ribosome-binding Antibiotics Increase Bacterial Longevity And Growth Efficiency

Read about how ribosome-binding antibiotics can enhance bacterial longevity and growth efficiency, challenging traditional views on antibiotic resistance.

NIH investigates multidrug-resistant bacterium emerging in community settings

NIH investigates emerging hypervirulent Klebsiella pneumoniae strains in community settings and their impact on infection severity and classification.

3 Reasons Why Pharmacies And Labs Should Partner To Improve Health Care

Discover key reasons why pharmacies and labs should collaborate to enhance healthcare services, address provider shortages, and improve patient outcomes.

Inside the Research: Studying Adherence to Sepsis Care Bundles Alongside The UK Sepsis Trust

A new study with the UK Sepsis Trust explores barriers to sepsis care bundle adherence in Europe and offers insights to improve sepsis management strategies.

Bringing Value To The Care Pathway: The Rising Role Of Rapid Diagnostics

This briefing explores how outcomes research can highlight the value of rapid diagnostics in combating antimicrobial resistance and supporting antimicrobial stewardship

Multidrug resistance pattern and molecular epidemiology of pathogens among children with diarrhea in Bangladesh, 2019–2021

A study in Bangladesh highlights alarming antibiotic resistance and viral co-infections in children with diarrhea, worsening the health threat.

A case for routine microbial diagnostics: Results from antimicrobial susceptibility testing in post-traumatic wound infections at a Ugandan tertiary care hospital

Learn about a study on antimicrobial resistance in post-traumatic wound infections in Uganda and the need for routine microbial diagnostics to guide treatment decisions.

Viewpoints Series: Clinical Mycology & Antimicrobial Resistance

Explore the growing threat of fungal infections in AMR, highlighting the challenges of detection, resistance, and the shortage of trained clinical mycologists.

A Common Allele of HLA is Associated with Asymptomatic SARS-COV-2 Infection

Research reveals that the HLA-B*15:01 allele may be linked to asymptomatic COVID-19 infection, potentially due to pre-existing T-cell immunity from previous coronaviruses.

Pharmacists Can Make a Difference in Antibiotic Stewardship at Discharge

ID pharmacists can improve antibiotic stewardship at discharge by identifying drug-related issues and optimizing prescriptions to reduce AMR risks.

Leveraging Artificial Intelligence in the Fight Against Infectious Diseases

Explore how artificial intelligence and machine learning are advancing the fight against infectious diseases, aiding in drug discovery, diagnostics, and outbreak control.

Mixed strain pathogen populations accelerate the evolution of antibiotic resistance in patients

Research reveals mixed strain populations accelerate AMR in ICU patients, highlighting the need to limit bacterial spread to combat resistance.

Policy Brief: Global Research Agenda for Antimicrobial Resistance in Human Health

Download the policy brief on the WHO’s Global Research Agenda for AMR in human health, outlining top research priorities to combat antimicrobial resistance by 2030.

Inside the Research: An Interview with ME Panel Study Authors Tristan Timbrook and Kyle Hueth

Learn how the BIOFIRE® ME Panel impacts patient length of stay and supports antimicrobial stewardship in this exclusive interview with study authors.

Clinical Epidemiology and Case Fatality Due to Antimicrobial Resistance (AMR) in Germany

This study highlights Germany's efforts to track AMR-related fatalities, improving national surveillance and antimicrobial stewardship strategies.

Change of Plans: Overview of Bacterial Taxonomy, Recent Changes of Medical Importance, and Potential Areas of Impact

This article explores recent changes in bacterial taxonomy, their impact on microbiology, antimicrobial stewardship, and infection prevention

The Economic Burden of Antibiotic Resistance: A Systematic Review and Meta-Analysis

Antimicrobial resistance significantly increases hospital costs and length of stay, with a global economic burden reaching billions annually.
Early empiric antibiotic use in COVID-19 patients: results from the international VIRUS registry

Early empiric antibiotic use in COVID-19 patients: results from the international VIRUS registry

Results from the Society of Critical Care Medicine Discovery VIRUS international COVID-19 Registry aim to determine the rate and factors associated with early empiric antibiotic (EEAB) treatment to help set goals for antimicrobial stewardship efforts, in the post-pandemic era.

Sepsis Alliance AMR Virtual Conference (April 26-27, 2023)

The Sepsis Alliance AMR Virtual Conference explores solutions for combating antimicrobial resistance and improving sepsis outcomes.

Optimizing Sepsis Outcomes and Antimicrobial Stewardship

Rapid diagnostics and antimicrobial stewardship are key to optimizing sepsis outcomes by enabling timely, targeted testing and treatment decisions.

How to Optimize Inside & Outside Lab Workflows: ECCMID 2023

Sandra Vallejo discusses optimizing lab workflows and improving collaboration with healthcare providers at ECCMID 2023

Impact of an antibiotic stewardship program on antibiotic utilization, bacterial susceptibilities, and cost of antibiotics

An antimicrobial stewardship program at An-Najah National University Hospital significantly reduced antibiotic use and costs, according to a recent study.

Antibiotic Susceptibility Patterns of Bacteria Associated with Sepsis among Hospitalized Patients in the Yaoundé University Teaching Hospital—Cameroon

A study in Cameroon highlights rising sepsis cases and AMR, emphasizing the need for surveillance, infection control, and antibiotic stewardship in hospitals.

Effect Of Intrapartum Azithromycin Vs Placebo On Neonatal Sepsis And Death: A Randomized Clinical Trial

A clinical trial in West Africa tests whether intrapartum azithromycin reduces neonatal sepsis and mortality, with additional evaluation of infection and fever rates.

Association Between Antimicrobial Stewardship Programs and Antibiotic Use Globally: A Systematic Review and Meta-Analysis

A review of 52 studies finds ASPs reduce antibiotic use in hospital and non-hospital settings, including WHO Watch List drugs.

The Increasingly Critical Role of Space Planning in Lab Operations

Innovative space planning is essential for lab safety, efficiency, and success, ensuring productivity and improved diagnostic outcomes

Viewpoints Series: How Advanced Analytics and Data Sharing Help Strengthen Chile’s Response to Antimicrobial Resistance

Chile uses cloud-based analytics to enhance antimicrobial stewardship by combining AMR data from over 40 hospitals for better patient and population outcomes.

Antimicrobial resistance in patients with COVID-19: a systematic review and meta-analysis

A review of 148 studies links COVID-19 hospital surges to rising antimicrobial resistance, with 60.8% of bacterial co-infections resistant to treatment.

Study Shows FDA-Approved TB Regimen May Not Work Against the Deadliest Form of TB Due to Multidrug-Resistant Strains

A study reveals the FDA-approved BPaL regimen may be less effective against multidrug-resistant TB meningitis due to limited drug penetration.

Expect Infectious Diseases to Skyrocket in the ICU

According to predictions from professor and practicing intensivist, Dr. Hannah Wunsch, war, multidrug resistance, climate change, emerging diseases, and reduced confidence in vaccination will be among the factors that influence an expected increase in infectious diseases in the ICU.

Improving Antimicrobial Stewardship for Respiratory Tract Infections

Rapid diagnostics help optimize antimicrobial stewardship for respiratory infections by identifying pathogens quickly, guiding treatment, and reducing AMR risks.

Performance of the VITEK® 2 Advanced Expert System (AES) as a Rapid Tool for Reporting Antimicrobial Susceptibility Testing (AST) in Enterobacterales from North and Latin America

This study highlights the effectiveness of the VITEK® 2 AES in providing rapid, accurate antimicrobial susceptibility testing for Enterobacterales isolates.

Diagnostics Are Essential for Improving Antimicrobial Stewardship and Combating Resistance

Global antimicrobial resistance (AMR) — the “silent pandemic” — is already causing a significant burden on healthcare systems, with COVID-19 only adding to the complexity and challenge of this global public health threat.

Diagnostics and Data Can Fill Gaps in Antimicrobial Stewardship Left by COVID-19

In this article, Brian Raux, PharmD, discusses the global impact COVID-19 has had on the rise of antimicrobial resistance (AMR) and the alarming increase of hospital-acquired infections (HAI).

The Importance of Diagnostics and AMS in the Context of COVID-19

COVID-19 may have accelerated AMR, highlighting the need for diagnostics and antimicrobial stewardship to manage bacterial coinfections

Webinar: Confronting the Impact of the Pandemic on ASP and Pneumonia

Explore the impact of the COVID-19 pandemic on antimicrobial stewardship programs and pneumonia diagnosis in this series featuring expert insights.

Foundation Aims to Help People 'See' C. difficile

The Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota interviewed Christian Lillis, founder of the Peggy Lillis Foundation, about the fight against Clostridioides difficile through education, awareness, and reducing unnecessary antibiotic use.

Taking the Guesswork out of ICU Pneumonia Diagnosis

Rapid diagnostics, like the BIOFIRE® FILMARRAY® Pneumonia Panel, are improving ICU pneumonia diagnosis in a multi-center trial across the UK.

COVID-19 in Infants Less than 3 Months: Severe or Not Severe Disease?

Explore a study on the severity of COVID-19 in infants under 3 months, comparing symptoms, outcomes, and antimicrobial stewardship approaches in this vulnerable group

Neurogenesis is disrupted in human hippocampal progenitor cells upon exposure to serum samples from hospitalized COVID-19 patients with neurological symptoms

Study reveals that inflammatory proteins in COVID-19 patients' blood may disrupt neurogenesis, leading to cognitive symptoms like delirium and memory loss.

Early Appropriate Diagnostics and Treatment of MDR Gram-negative Infections

A group of global experts from Italy, Lebanon, Thailand, India, the U.S., Colombia and China speak about the need for rapid diagnostic tests and efficient laboratory workflows for multi-drug resistant (MDR) Gram-negative infections.

Gaps and Barriers in the Implementation and Functioning of Antimicrobial Stewardship Programs

Researchers around the world worked together to identify educational gaps and systemic barriers obstructing adherence to antimicrobial stewardship (AMS) principles in France, India, Mexico, and the United States.

Neonatal Sepsis: The New Threat Posed By Superbugs

Superbugs are worsening neonatal sepsis outcomes in South Asia where antibiotic resistance is driving high mortality rates in newborns with severe infections.

CDC 2022 Special Report: COVID-19 U.S. Impact on Antimicrobial Resistance

The CDC's 2022 special report reveals a rise in multi-drug resistant organisms (MDROs) in U.S. hospitals during COVID-19, highlighting the impact of increased antimicrobial use.

Interpreting Antimicrobial Resistance Results and the Impact of New Molecular Technologies

Discover how new molecular technologies help labs interpret antimicrobial resistance results and support antibiotic stewardship efforts.

AMR and Associated Risk Factors of Gram-Negative Bacterial Bloodstream Infections in Tikur Anbessa Specialized Hospital in Ethiopia

Researchers at TISH in Ethiopia used bioMérieux AST to study Gram-negative BSIs, finding high AMR rates in pediatric and ICU patients, urging intervention.

Bridging the Gap: An Interview with Microbiologist Andrea Prinzi

In this interview, microbiologist Andrea Prinzi discusses how diagnostic data can unite lab professionals, clinicians, and pharmacists to enhance antimicrobial stewardship.

Clinical Sepsis Phenotypes in Critically Ill COVID-19 Patients

Explore the comparison of clinical sepsis phenotypes in critically ill COVID-19 patients and implications for predicting outcomes, treatment, and personalized medicine.