GENE-UP® Pathogenic E. coli
FROM INSIGHT TO ACTION: EHEC INTELLIGENCE YOU CAN TRUST
GENE-UP® Pathogenic E. coli (PEC) brings accurate, reliable, and easy-to-use detection of high-risk E. coli strains, including O157:H7.
GENE-UP® PEC reduces current testing ambiguity, accelerates decision-making, and limits product diversion. That means fewer delays, fewer disruptions, and greater assurance for your supply chain
With GENE-UP® PEC, you can Prevent, Enhance, and Control — replacing complexity with clarity to detect what matters
- Overview
- Behind The Science
- Services
- Resources
- Get Started Today
Product Details
GENE-UP® PEC is an AOAC® approved that dramatically reduces unconfirmed positive rates, thanks to our cutting-edge molecular approach. With PEC, you can bring your operations increased profits, increased protection, and increased peace of mind.
With a simple, streamlined workflow that can be easily applied across food operations susceptible to EHEC contamination, GENE-UP® PEC improves confidence in detection of true EHEC. It reduces the time needed for screening and confident release of PEC negative products, minimizing unconfirmed positives that would lead to unnecessary time and cost spent holding products awaiting further confirmation.
Features & Benefits
- ACCURATE: Reduce non-confirmed positives up to 60%1
- PROFITABLE: Release product faster
- SAFE: Detect what matters and avoid costly recalls
- RAPID: One hour to a confident decision2
- SIMPLE: Avoid unnecessary and laborious confirmations
- SUSTAINABLE: Stay ahead of evolving regulatory expectations
- RELIABLE: Proven science through collaborative innovation
- SUPPORT: Full access to bioMérieux scientific expertise
1. USDA-ARS data when compared to current PCR technologies: https://www.mdpi.com/2304-8158/14/3/382
2. GENE-UP® Instructions For Use
Unmatched Accuracy
According to the USDA (Constituent Update - June 28, 2024), GENE-UP® PEC is more efficient than existing testing methods currently in use, leading to significant reductions in non-confirmed positives and in time spent holding product while awaiting secondary result confirmation. This ultimately reduces testing costs and brings more confidence to your brand.
Because of the increased accuracy of GENE-UP® PEC in detecting adulterant E. coli strains, the FSIS has stated that GENE-UP® PEC-screened negative samples can be considered negative for typical EHEC, helping producers release products faster and increasing efficiency. The test kit is designed to complement and enhance current methods, enabling food safety programs to be both more flexible and more precise.
What the heck is PEC? Find out in this short video; and learn how our GENE-UP® PEC assay allows for smarter testing through the power of co-location.
A Smarter PCR Assay Enabling the Power of Co-Location
Most commercially available PCR tests can detect the presence of both Shiga toxin (stx) genes and intimin (eae) genes but are incapable of indicating whether these genes are co-located within a single organism and indicate a true pathogenic E. coli.
Historically there are inherent limitations of screening for the eae and stx genes that, when co-located within an E. coli bacteria, can cause human illness. Because of the way these PCR tests are inherently designed, it can be difficult to determine whether the conditions exist within a single cell that will truly lead to an adulterant strain. This can lead to high numbers of non-confirmed positives, which means unnecessary effort, time, and money spent on confirmation processes, increased time-to-market, and product having to be potentially scrapped or diverted.
GENE-UP® PEC utilizes a novel molecular diagnostic target to rapidly detect strains that contain both stx genes and eae genes within the same organism, significantly reducing unconfirmed positive results. Until now, no other real-time PCR technology has been able to deliver this level of precision and insight.
Because of its high specificity and strong correlation with genomic co-location of stx and eae genes, GENE-UP® PEC negative samples can can be considered negative for typical EHEC.
Services: Feasibility, Validation, and Instrument Support
Your productivity and product quality are our priority. At bioMérieux, we aren’t just selling fast and reliable solutions – our technical team and scientific experts are fully committed to help you get the most out of your equipment, to ensure the continuity of your operations.
From feasibility, to installation and IT integration and training, our entire range of services can be customized to your needs throughout your whole journey with us, focusing on your core business and optimizing your resources.
Downloads
Contact Us and Start Today
Unlock reliable, easy-to-use detection for the top pathogenic strains. Get in touch with our team using the form below and one of our experts will be in touch with details on GENE-UP® PEC using the contact information you provide. By providing your information, you agree to receive additional emails from bioMérieux about PEC detection
