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AmPORE-TB

Rapid characterization of mutations associated with antimicrobial resistance in Mycobacterium tuberculosis complex

AmPORE-TB (for research use only) supports the fight against tuberculosis with the power of real-time nanopore sequencing. Its streamlined workflow is strengthened by bioMérieux’s global service network and trusted expertise in antimicrobial resistance and stewardship.

Designed by Oxford Nanopore Technologies. Not available in the United States.

Overview

Deliver rapid drug-resistant tuberculosis (DR-TB) data with AmPORE-TB

Characterize 24 resistance genes in Mycobacterium tuberculosis complex with an efficient next-generation sequencing (NGS) workflow. Combine fast library preparation with on-demand sequencing and hands-off, comprehensive onboard analysis to deliver comprehensive, accurate reports within the same day.

As an exclusive distributor and support partner of Oxford Nanopore Technologies, bioMérieux brings to laboratories the complete solution, for research use only, including the GridION AmPORE-TB nanopore sequencing device, AmPORE-TB reagents, and the software.

Fast, easy workflow to assess DR-TB in TB positive samples

Efficient workflow    

  • Less hands-on time, easy NGS workflow for same-day results
  • Targeted nanopore sequencing – scalable & flexible up to 22 samples per run
  • Benchtop device for any lab and reusable flow cells (GridION AmPORE-TB)
  • Built-in software for automated analysis execution after sequencing – no cloud connectivity required
  • Workflow compatible with DNA directly extracted from sputum

Reliable results

  • Targeted next-generation sequencing method recommended by WHO for Antimicrobial Resistance (AMR) testing accuracy1
  • In-depth per-sample results for research insights
  • AMR data for 24 resistance genes, >1,200 drug resistance-associated mutations
  • Clear quality control status including spoligotype lineage and HSP 65 NTM marker

Our commitment to global health

bioMérieux works hand in hand with local organizations, international aid organizations, governmental partners, Non-governmental organizations (NGOs), foundations and funding agencies globally to bring diagnostics solutions equitably to regions most in need. Under the guidance of our dedicated Global Health Department, we support implementation and long-term sustainability of our solutions for infectious diseases and Antimicrobial Stewardship.

Our commitment to supporting the fight against TB is precisely aligned with our overall commitment to Global Health.

Reference

1. World Health Organization operational handbook on tuberculosis. Module 3: Diagnosis – Rapid diagnostics for tuberculosis detection, third edition. 2024.



Designed by Oxford Nanopore Technologies, manufactured by Oxford Nanopore Diagnostics - a fully owned subsidiary of Oxford Nanopore Technologies plc. Oxford Nanopore Technologies products are not intended for use for health assessment or to diagnose, treat, mitigate, cure, or prevent any disease or condition.

AmPORE-TB and GridION are registered trademarks or trademark applications of Oxford Nanopore Technologies plc in various countries.

Reagents

AmPORE-TB kit
Reference: OND-S-ATB01-RGL
Allows preparation of a total of 96 samples (incl negative and positive controls)

 

Flowcell R9
Reference: OND-FM001-RGL
Sequencing device
Can be used for 1 to 4 runs
Run on the GridION

 

Flow Cell Recalibration kit
Reference: OND-E-FRK01-RGL
Used to wash the flow cell in between usage

amPORE-TB

Services & Support

bioMérieux expertise
 
  • More than 60 years as a global leader in infectious disease diagnostics
  • Specialized expertise in antimicrobial resistance and stewardship
  • Broad network ensuring reliable delivery and expert service in 160+ countries
  • Bringing a complete solution to support laboratories globally in the fights against resistant Tuberculosis (TB)

Worldwide Network

  • High quality of skilled field application specialist
  • High level of responsiveness
  • On site training and maintenance

Comprehensive Service Contracts Ensure Optimal Performance & Reliability

  • On-site installation and workflow training
  • Maintained Workflow: Supports continuous lab operations with quick issue resolution
  • Instrument Swap: Replacements to minimize disruptions

Specs & Resources

Technial specifications

GridION Q-line for AmPORE-TB:

ComponentSpecification
Size and weightH 220 x W 365 x D 370 mm, 14.4 kg
Compute spec7 TB SSD storage, 64 GB RAM, Intel i9 CPU for OS and orchestration, basecalling accelerator
Pre-loaded softwareLinux OS, GridION OS, sequencing software
Environmental conditions

System functiona range +5 °C to +40°C

Deigned to sequence at +18°C to +25°C

The end-to-end work­flow, inclusive of reagents, GridION device, and software, is manufactured under ISO 13485.

RESOURCES

Filename
LUMED-APSS-Brochure.pdf
Size
2 MB
Format
application/pdf
AmPORE-TB Brochure

AmPORE-TB Brochure


See more technical documentation about AmPORE-TB on the Oxford Nanopore Technologies website: Product documentation - AmPORE-TB

Filename
Brochure_AmPORE-TB_PDF-Digital_BMX.1.162451__GLB.pdf
Size
977 KB
Format
application/pdf
Filename
Brochure_AmPORE-TB_PDF-Digital_BMX.1.162451__GLB.pdf
Size
977 KB
Format
application/pdf