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The Hunt for the Missing Endotoxin

In this white paper, you’ll learn about the causes contributing to low endotoxin recovery (LER), the impact it creates, and solutions that can help address the issues it generates. The advantages and disadvantages of developing de-masking protocols in-house are explored, along with how the ENDO-RS® de-masking tool kit can help simplify the process from start to finish. The white paper also outlines the pros and cons of outsourcing de-masking projects, what to look for in a third-party company, and why bioMérieux can be a trusted partner for de-masking protocol development. Insights from Dr. Christian Faderl provide additional perspective on masked endotoxins and strategies pharmaceutical manufacturers can use to effectively tackle LER.

Is Outsourcing the Solution to Low Endotoxin Recovery (LER)?

Don’t miss this opportunity to stay ahead in endotoxin detection. Complete the form below to access the white paper, which will be sent directly to your email after submission. By providing your information, you agree to receive additional emails from bioMérieux about endotoxin testing.

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Tackle LER Challenges in Endotoxin Testing

ON-DEMAND WEBINAR

Unmasking Endotoxins: A Sample Preparation Strategy To Overcome LER

This expert webinar dives into the science behind LER, its regulatory implications, and proven strategies to unmask endotoxins effectively.

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ENDOXPERTS™ Services

ENDOXPERTS™ Endotoxin Services by bioMérieux provide routine testing and feasibility studies as well as specialized services for analytical issues such as LER. Our work for leading pharmaceutical companies has resulted in validated methods for LER, fulfilling regulatory requirements. 

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WHITE PAPER

Low Endotoxin Recovery: A Comprehensive Overview for Biologic Drug Manufacturers

Endotoxin detection is an integral part of the quality control process, and LER muddles the reliability of results, which can result in risks to patient safety and noncompliance with regulations. 

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WHITE PAPER

Low Endotoxin Recovery: A Mitigation Approach Case Study

This white paper discusses the Low Endotoxin Recovery (LER) phenomenon in the drug testing and mitigation approach using the ENDO-RS® kit and ENDOLISA® assay for detecting endotoxin interference. Authors Dr Christian Faderl and Kevin L. Williams detail the steps for conducting a demasking study and walk through the process, providing a comprehensive case study.

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