Global Antibiotic Resistance Surveillance Report 2025
Published on : December 2025
SUMMARY
World Health Organization | October 2025
Urgent Update. The 2025 WHO Global Antibiotic Resistance Surveillance Report, based on data from over 23 million infections across 104 countries, reveals that one in six bacterial infections—and one in three urinary tract infections—were caused by bacteria resistant to antibiotics. Median resistance was most common in UTI and bloodstream infections, and less so in gastrointestinal infections. Between 2018 and 2023, antimicrobial resistance (AMR) increased in 40% of pathogen-antibiotic combinations monitored, with annual relative increases ranging from 5 to 15%, intensifying reliance on second-choice and last-resort antibiotics and highlighting critical vulnerabilities in diagnostic and surveillance capacities worldwide.
This report highlights the disproportionate burden of AMR in low- and middle-income countries with fragile health systems, and calls for urgent investment to expand diagnostic infrastructure, strengthen antibiotic stewardship (AMS), and scale up comprehensive, quality AMR surveillance to guide effective treatment and policy.
FEATURED EXPERT
• World Health Organization
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Read the WHO report now to learn how these trends could impact clinical outcomes, stewardship, and your own practices.
