Implementing Dynamic Automated Flow Cytometric Analysis for Rapid Cell Therapy Manufacturing QC
Automating flow cytometric analysis enables all levels of technicians to generate accurate and precise cell enumeration and phenotyping results in real time, providing actionable in-process information.
Implementing Dynamic Automated Flow Cytometric Analysis
- Filename
- Accellix-2024-CAR-TCR-Automated-Analysis-Poster.pdf
- Size
- 1 MB
- Format
- application/pdf
Summary
- Accellix offers assay-specific autoclassification software that can be tailored to meet requirements for different cell therapy products and workflows, generating automated results at the end of each run for real-time evaluation.
- Parameterization of cell density profiles and other characteristics allow unsupervised algorithms to dynamically identify, classify, and enumerate pre-defined cell subsets, mitigating the need for manual adjustment of gates and subjective data interpretation.
- Linear regression and Bland-Altman analyses show strong agreement between Accellix autoclassification and manual analysis results for 3 off-the-shelf assays and 3 custom CAR-T assays.
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