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5 Targets or 15 Targets—You Decide

An evolving world deserves evolved diagnostics. As the leader in syndromic PCR testing, bioMérieux has evolved our point-of-care respiratory testing solution by developing new products with clinicians and their patients in mind. bioMérieux is pleased to announce a revolutionary portfolio of versatile, respiratory PCR tests, the BIOFIRE® SPOTFIRE® Respiratory (R) Panel Mini and BIOFIRE® SPOTFIRE® Respiratory (R) Panel, which give clinicians syndromic options as they care for a variety of patients. These tests run on a new, fast, easy-to-use BIOFIRE® SPOTFIRE® System.

Product Overview


The SPOTFIRE System is the latest advancement in molecular infectious disease diagnostics. It is designed to run the SPOTFIRE R Panels.

  • Requires minimal bench top space with the ability to scale up to four modules vertically, enabling customizable throughput
  • Module random access allows running up to 4 tests at the same time
  • Easy to use with an intuitive system interface and streamlined workflow
  • Can be used by any healthcare profession in any healthcare setting
  • Seamlessly connects with Point of Care data management systems and other compatible systems and software

1. Calculation based on running the BIOFIRE® SPOTFIRE® R PANEL (~15 minutes) in an 8 hour shift.

SPOTFIRE Respiratory (R) Panel

1 PCR Test. 15 Targets. ~15 Minutes.

The SPOTFIRE R Panel brings diagnostic power to clinicians via a PCR-based expanded syndromic approach. In other words, the SPOTFIRE R Panel combines symptom-driven testing for a broad grouping of probable respiratory pathogens into one rapid test that aids in the diagnosis of patients experiencing signs or symptoms of respiratory tract infections, maximizing the chance of getting an actionable answer in a clinically relevant timeframe.

See Technical Details tab for full panel menu.


SPOTFIRE Respiratory (R) Panel Mini

1 PCR Test. 5 Targets. ~15 Minutes.

The SPOTFIRE R Panel Mini brings the power of targeted syndromic testing via PCR results to the front line. It tests for the 5 most probable viruses that cause respiratory tract infections, including influenza, rhinovirus, respiratory syncytial virus, and SARS-CoV-2. This panel runs on the easy-to-use SPOTFIRE System, which provides results in about 15 min.

See Technical Details tab for full panel menu.


Rethink the Power of Diagnostics with the SPOTFIRE Respiratory Solution to Potentially:

Inform Clinical Decisions

  • High sensitivity, specificity, and reliability provides results clinicians can trust
  • Contrary to tests that only detect the flu, SARS-COV-2, and/or RSV, a syndromic panel provides a fuller picture that may help inform patient management decisions

Optimize Operations

  • The simplified workflow and quick turnaround time enable rapid and accurate answers during the patient visit, while reducing the need for callbacks or expensive and slow send-out testing
  • This easy-to-use solution enables users of all skill levels to prepare and run samples

Optimize Antimicrobial Stewardship

  • Receiving accurate, comprehensive results in a clinically actionable timeframe may inform diagnoses while optimizing care and antimicrobial stewardship

Improve Patient Satisfaction

  • Using the right test, the first time to detect multiple pathogens may result in reduced follow-up appointments, swabbing, and testing, which could improve patient comfort, experience, and convenience

Product availability varies by country. Consult your bioMérieux representative. 


1. Overall performance and SARS-CoV-2 performance based on the prospective clinical study for the BIOFIRE SPOTFIRE Respiratory Panel.

Technical Details

SPOTFIRE Respiratory Panel:

  • Sample Type: Nasopharyngeal swab in 1-3 mL of viral transport media
  • Hands-on time: 1-2 minutes
  • Overall Peformance:1 PPA: 98.5%, NPA: 99.1%
  • SARS-CoV-2 Performance:1 PPA: 97.3%, NPA: 99.4%

SPOTFIRE Respiratory Panel Mini:

  • Sample Type: Nasopharyngeal swab in 1-3 mL of viral transport media
  • Hands-on time: 1-2 minutes
  • Overall Performance:1 PPA: 98.7%, NPA: 98.4% 
  • SARS-CoV-2 Performance:1 PPA: 97.3%, NPA: 99.4%

SPOTFIRE Respiratory Panel Menu


  • Adenovirus
  • Coronavirus SARS-CoV-2
  • Coronavirus (seasonal)
  • Human metapneumovirus
  • Human rhinovirus/enterovirus
  • Influenza A virus
    • Influenza A virus A/H1-2009
    • Influenza A virus A/H3
  • Influenza B virus
  • Parainfluenza virus
  • Respiratory syncytial virus


  • Bordetella parapertussis
  • Bordetella pertussis
  • Chlamydia pneumoniae
  • Mycoplasma pneumoniae

SPOTFIRE Respiratory Panel Mini Menu


  • Coronavirus SARS-CoV-2
  • Human rhinovirus
  • Influenza A virus
  • Influenza B virus
  • Respiratory syncytial virus

Product Information

BIOFIRE SPOTFIRE Respiratory Panel Kit 42446130-Pack
BIOFIRE SPOTFIRE Respiratory Panel Mini Kit 42458930-Pack
SPOTFIRE RSP Pos & Neg ControlsM4252 boxes (1 x M42638, 1 x M42738) 
SPOTFIRE RSP Positive ControlsM426381 box (6 tubes)
SPOTFIRE RSP Negative ControlsM427381 box (6 tubes)
NATtrolTM Respiratory Verification PanelNATRSP-BIO1 Panel
NATtrol™ Respiratory Verification Panel MiniNATRMP-BIO1 Panel
BIOFIRE SPOTFIRE Respiratory Panel, Verification Kit 4245951 x NATRSP-BIO, 5 x M425, 3 x 424461
BIOFIRE SPOTFIRE Respiratory Panel Mini, Verification Kit 4245961 x NATRMP-BIO, 5 x M425, 3 x 424461 

Service & Support

With the urgent nature of patient and community care, we take pride in addressing all concerns quickly and accurately. bioMérieux is dedicated to providing world class customer support 24 hours a day, 7 days a week, 365 days a year.

For assistance please contact our customer technical support team at:

To order, contact your regional sales representative or use the following contact information: