July 02, 2025
A Balancing Act: Fighting Sepsis and Antimicrobial Resistance at the Same Time
Studies show that the rapid administration of antibiotics has been generally associated with a decrease in deaths among hospitalized patients with sepsis. However, the need to quickly administer effective therapy can lead to clinicians turning to broad-spectrum antibiotics, which can exacerbate antimicrobial resistance (AMR). Because AMR is a major healthcare concern—including for patients with sepsis—improving the alignment between sepsis protocols and antimicrobial stewardship (AMS) guidelines is important for patient care.