Validation of a Rapid, Fully Automated Mycoplasma Detection System
The BIOFIRE® Mycoplasma Detection System can facilitate screening at various stages of the manufacturing process for low-level mycoplasma contamination in a wide range of possible sample types. With less than 5 minutes of hands-on time and a fully automated test system, more frequent testing near the site of manufacture will be possible to improve surveillance for potential mycoplasma contamination events.
15 different PCR assays are included in every run to cover the wide genetic diversity of the Mollicutes class, including species of the genera Acholeplasma, Entomoplasma, Mesoplasma, Mycoplasma, Phytoplasma, Spiroplasma, and Ureaplasma. Three internal controls ensure the reliability of results by monitoring all aspects of pouch function, from sample extraction through amplicon detection.