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VIDAS® TBI (GFAP, UCH-L1)

Quickly determine whether your mTBI patient really needs a head CT scan

VIDAS TBI is a blood-based biomarker immunoassay test that quickly and accurately rules out traumatic intracranial lesions (ICLs), enabling confident decisions and efficient triage for adult patients suspected of having mild traumatic brain injury (mTBI).1

  

Disclaimer: Product availability varies by country. Please consult your local bioMérieux representative for product availability in your country.

VIDAS® TBI (GFAP, UCH-L1)

Why VIDAS TBI?

Standard patient assessment methods for mTBI can be subjective, time-consuming, and may lead to over-imaging.2,3 Over 90% of head CT scans in mTBI patients show no abnormalities.3

VIDAS TBI enables smarter triage by:

  • Providing objective, accurate information to safely rule out ICLs1
  • Supporting head CT decision-making in adults within 12 hours of injury1
  • May reduce unnecessary CT scans4

GFAP and UCH-L1 Biomarkers

VIDAS TBI simultaneously tests two blood-based brain biomarkers that are released from different cell types in the minutes and hours following a traumatic brain injury.

GFAP-UCH-L1-Biomarkers

How to interpret VIDAS TBI Results

The VIDAS TBI immunoassay test is designed for easy interpretation. 

VIDAS TBI Result

What it Means

GFAP Negative and UCH-L1 Negative

Indicates the absence of ICL, which may rule out the need for a head CT scan

GFAP and/or UCH-L1 Positive

Indicates a head CT scan may be needed

VIDAS TBI Performance

The assay is approved for adult patients (>18 or over), with a testing window of up to 12 hours post-injury.1

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Speed

VIDAS delivers results in ~39 minutes1

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Accuracy

Sensitivity 96.7%1
Negative predictive value 99.5%1

vidas-3-instrument

The VIDAS® 3 Immunoassay Analyzer

VIDAS 3 is the new-generation VIDAS analyzer that is designed with your lab’s specific needs and workflow in mind. It is equipped with increased automation, traceability and connectivity for greater productivity.† VIDAS 3 helps you provide precise and accountable test results for the benefit of clinicians and their patients:5

  • Reliable and easy-to-use instruments with random access and small footprint. 
  • Well adapted to rapid response laboratories.
  • Factory-calibrated, Single-dose tests which reduce the need for additional controls.
  • Short time to result.

†Compared to MINI VIDAS® and VIDAS 30®

Learn More

Technical Specifications

Assay

Reference

Tests per Kit

Code

Time to Result

Decisional Cut-Offs

VIDAS® TBI (GFAP, UCH-L1)

423615-01

60

GFAP
UCH
1 patient test = 1 GFAP + 1 UCH-L1

39 min

GFAP= 22pg/mL
UCH-L1 = 327 pg/mL

Helpful Resources

References:

  1. VIDAS® TBI (GFAP, UCH-L1) [package insert]. Lyon, France: bioMérieux; 2023.
  2. Michelson EA, et al. West J Emerg Med. 2018 Jul;19(4):635-640. doi: 10.5811/westjem.2018.5.37293. Epub 2018 Jun 13. PMID: 30013697; PMCID: PMC6040897.
  3. Korley, F.K., et al., Emergency Department Evaluation of Traumatic Brain Injury in the United States, 2009-2010. J Head Trauma Rehabil, 2016. 31(6): p. 379-387.
  4. Bazarian JJ, et al. Lancet Neurol. 2018;17(9):782-789.
  5. bioMérieux. VIDAS® 3 User Manual US Version.