Are Urinary Tract Infections a problem?
Urinary tract infections (UTIs) are among the most common infections in the clinical environment. Most UTIs are caused by Gram-negative bacteria, most commonly Escherichia coli or species of Klebsiella, Proteus, Pseudomonas, or Enterobacter, although other strains, such as Staphlyococcus and Serratia, are emerging1. Although UTIs are usually uncomplicated and can be treated with a short course of antibiotics, they can be painful and recurrent.
Moreover, UTIs are involved in up to 40% of healthcare-associated infections (HAI), principally due to catheter use2. UTIs are increasingly caused by drug-resistant bacteria, making it especially important to identify the pathogen involved and resistance mechanisms, to effectively orient antibiotic therapy.
In the United States alone, UTI-related symptoms lead to almost 10 million office visits and around 3 million emergency visits each year. In the UK, 1%–3% of all medical consultations are due to UTIs. It is the second most common reason for prescribing antibiotics in the UK.3
What challenges are labs facing with respect to UTIs?
Urine represents the main and biggest sample volume in the microbiology labs. Streamlined lab workflow is critical to handle the large amount of volume every day. Plus, patient care is reliant on rapid results and accurate reporting from the lab.
Ultimately, it is crucial that labs of all sizes implement cost effective solutions offering optimized workflow that not only reduce the amount of handling steps but reduce the time to accurate result to improve antimicrobial stewardship worldwide.
How can bioMérieux help with UTI Management?
What if your lab could accelerate identification (ID) / antimicrobial susceptibility testing (AST) and report actionable results to clinicians for better patient management?
bioMérieux offers a full urinary tract infection diagnostic solution to meet the needs of your lab, small or large.
Our solution addresses the main challenges by offering:
- Optimized workflow by reducing handling steps throughout the process and automated unloading of negative cultures
- High Productivity for faster results in comparison to routine workflow with high throughput, automation, and integration
- Clear identification; improved detection of mixed urine cultures
- Rapid AST and MIC for personalized treatment
- Advanced result rules-based expertise to provide clinicians with optimal information, with real-time alerts on MDRO and reporting on potential HAIs
Depending on your needs, key features of our UTI Solution include:
- 20% reduced turnaround time (TAT) with direct ID of E coli. with CHROMID® CPS ELITE4
- Throughput up to 150 urine specimens/hour with continuous loading from WASP®
- WASPLab®’s Early reading 12h protocol with CHROMID® CPSE plate
- Automated sorting of plates and autorelease of results with PhenoMATRIX® Plus
- Automated selection of isolated colonies to automatize the picking with Colibri™ system
- Automated AST testing with results in 5-8 hours with VITEK® 2 – with a comprehensive menu featuring specific UTI and MDRO cards
- Manual AST testing with results in 16-24 hours with ETEST® - with specific UTI drugs and extended MIC calling range for challenging situations
- High-confidence identification within minutes and 16-slide capacity with VITEK® MS Prime
Immersive video UTI management
Immersive video UTI management
Urinary Tract Infection - Our Diagnostic Offer
bioMérieux offers a full UTI diagnostic solution with system/reagent compatibility from sample collection to AST results and reporting.
Disclaimer: Product availability varies by country. Please consult your local bioMérieux representative for product availability in your country.
bioMérieux provides early reading protocol with the fastest validated urine culture workflow with CHROMID® CPS® Elite media.
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CHROMID®
Chromogenic Media for Organism Isolation and Identification
Innovative and extensive range of chromogenic media for the simultaneous culture and identification of microorganisms in clinical specimens.
Useful Resources on Urinary Tract Infections
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References
1. Flores-Mireles AL, Walker JN, Caparon M, Hultgren SJ. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015 May;13(5):269-84. doi: 10.1038/nrmicro3432. Epub 2015 Apr 8. PMID: 25853778; PMCID: PMC4457377.
2. Chenoweth CE, Gould CV, Saint S. Diagnosis, management, and prevention of catheter-associated urinary tract infections. Infect Dis Clin North Am. 2014 Mar;28(1):105-19. doi: 10.1016/j.idc.2013.09.002. Epub 2013 Dec 8. PMID: 24484578; PMCID: PMC9580547.
3. Paul R. State of the Globe: Rising Antimicrobial Resistance of Pathogens in Urinary Tract Infection. J Glob Infect Dis. 2018 Jul-Sep;10(3):117-118. doi: 10.4103/jgid.jgid_104_17. PMID: 30166807; PMCID: PMC6100332.
4. K. Manickam et al, JCM, 2013.